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The Diabetes Educator, Vol. 28, No. 2, 269-277 (2002)
DOI: 10.1177/014572170202800212

Insulin Lispro Update

Jerry D. Meece, RPh, FACA, CDE

Clinical Services at Plaza Pharmacy and Wellness Center in Gainseville, Texas.

R. Keith Campbell, RPh, FASHP, CDE

Washington State University, Department of Pharmacy Practice, Wegner Hall #147, Pullman, WA 99164-6510 rkcamp{at}wsu.edu

PURPOSE

This paper provides a review of the literature and clinical studies for insulin lispro and updated information on its advantages over regular insulin for various populations of people with diabetes.

METHODS

Information was gathered from a search of Medline articles and from review of clinical studies.

RESULTS

Patients in various special populations using insulin lispro, with proper adjustment of basal insulin, had a greater reduction in hemoglobin Al C and fewer episodes of hypoglycemia than patients on regular insulin.

CONCLUSIONS

More recently published literature shows that due to its faster onset and shorter duration of action, insulin lispro is useful for not only lowering Al C values, but also for reducing hypoglycemic events in various populations with diabetes, including pediatric and pregnant patients, those with gastroparesis, and insulin pump users.


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